| Cold Opening | Vice Presidential Debate |
| Alec Baldwin | ... | Donald Trump Live |
| Beck Bennett | ... | Mike Pence |
| Mikey Day | ... | Tim Kaine |
| Steve Higgins | ... | announcer Voice |
| Kate McKinnon | ... | Hillary Clinton |
| Cecily Strong | ... | Brooke Baldwin |
| Melissa Villaseñor | ... | Elaine Quijano |