| Sketch | Brain Space |
| James Franco | ... | moderator |
| Nicki Minaj | ||
| Vanessa Bayer | ... | Lex |
| Aidy Bryant | ... | Rhombus |
| Taran Killam | ... | Cal Hockley |
| Taran Killam | ... | Darren Hayes |
| Kate McKinnon | ... | Kevin McCallister |
| Bobby Moynihan | ... | Lance Ito |
| Jay Pharoah | ... | Will Smith#6 |
| Cecily Strong | ... | Mrs. Mancinelli |
| Beck Bennett | ... | Ashley Parker Angel |
| Pete Davidson | ... | Jeremy |
| Kyle Mooney | ... | Chris Kirkpatrick |
♬'N Sync - "Bye Bye Bye"