| Game Show | I'm Gonna Have Sex With Your Wife |
| Bradley Cooper | ... | Danny Lane |
| Fred Armisen | ... | Michael Vodner |
| Will Forte | ... | Ron Stillwell |
| Bill Hader | ... | Tommy McCafferty |
| Michaela Watkins | ... | Catherine Stillwell |
| Kristen Wiig | ... | Jennifer McCafferty |
| Casey Wilson | ... | Michael's wife |
| Steve Higgins | ... | announcer Voice |