April 21, 2007#1
| Cold Opening | White House Press Conference |
| Charles Schumer | Live | |
| Jim Downey | ... | announcer Voice |
| Will Forte | ... | Jim |
| Bill Hader | ... | Tony |
| Maya Rudolph | ... | Janet |
| Jason Sudeikis | ... | George W. Bush |
| Kenan Thompson | ... | reporter |
| Kristen Wiig | ... | Susan |
| Phil Hymes | ... | Dr. Lawrence Siskind Still |