| Sketch | The Big Tree |
| Teri Garr | ... | Stacey Drexel Stompanato |
| Joan Cusack | ... | Carla Stone |
| Robert Downey Jr. | ... | Nicky Stompanato |
| Nora Dunn | ... | Alexandra Drexel |
| Anthony Michael Hall | ... | Dr. Cory Whitcomb |
| Jon Lovitz | ... | Victor Drexel |
| Dennis Miller | ... | Senator Creighton Dunbar |
| Randy Quaid | ... | Ted Caruthers |
| Terry Sweeney | ... | Denny Fairchild |
| Danitra Vance | ... | Janet Rhodes |
| Lanier Laney | ... | guest |
| Carol Leifer | ... | guest |
| Don Pardo | ... | announcer Voice |
| Joe Forristal | ... | guest |