| Show | Sex After 50 |
| Seth MacFarlane | ... | Junior Grunions |
| Fred Armisen | ... | Rodger Brush#5 |
| Vanessa Bayer | ... | Sheila Sheath |
| Bill Hader | ... | Leonard#4 |
| Bobby Moynihan | ... | Wayne Sheath |
| Kate McKinnon | ... | Connie Judith Eame |
| Kate McKinnon | ... | announcer Voice |
| Tim Robinson | ... | Mark |
| Cecily Strong | ... | Dr. Lene Burrows Fashunta Still |
| Guy Veryzer | ... | audience member |