| Cold Opening | Democratic Debate |
| Fred Armisen | ... | Mike Bloomberg Live |
| Alec Baldwin | ... | Donald Trump Live |
| Larry David | ... | Bernie Sanders Live |
| Rachel Dratch | ... | Amy Klobuchar Live |
| Maya Rudolph | ... | Kamala Harris Live |
| Jason Sudeikis | ... | Joe Biden Live |
| Heidi Gardner | ... | Judy Woodruff Live |
| Colin Jost | ... | Pete Buttigieg Live |
| Kate McKinnon | ... | Elizabeth Warren |
| Kate McKinnon | ... | Nancy Pelosi Live |
| Cecily Strong | ... | Tulsi Gabbard |
| Bowen Yang | ... | Andrew Yang Live |
| Steve Higgins | ... | announcer Voice |